July 1, 1979Open Access

On the molecular-weight-dependence of the anticoagulant activity of heparin

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

The inactivation of thrombin and factor Xa by antithrombin was determined in the presence of heparin fractions of different molecular weights and with high affinity for antithrombin. The ability to potentiate the inactivation of either coagulation factor increased with increasing length of the polysaccharide chain.

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo

Cite This Study

Thunberg et al. (Sun,) studied this question.

synapsesocial.com/papers/6a19ff9f0ef26ba216f6a2a6 https://doi.org/https://doi.org/10.1042/bj1810241

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1The separation of active and inactive forms of heparin1976 · 492 citations
2Bovine Factor X. II. Characterization of purified Factor X. Alterations in zone electrophoretic and chromatographic behavior occurring during purification1968 · 95 citations
3A catalytic role for heparin1978 · 129 citations
4Chemistry of the hemostatic mechanism and its relationship to the action of heparin.1977 · 108 citations
5The Chemical Physiology of Mucopolysaccharides1968 · 235 citations

Preguntar a la IA

Me gusta

Guardar

Ver artículo completo