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Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide | Synapse

May 1, 1977European Journal of Immunology171 citations

Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide

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ACAntónio CoutinhoChampalimaud Foundation LFLuciana ForniUmeå University FMFritz MelchersLeibniz Association

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Resumen

Splenic B cells C57BL/10ScCr mice fail to respond to the mitogenic principle of lipopolysaccharide (LPS), and do not express a serologically defined "LPS receptor". In contrast, polyclonal B cell responses to both purified protein derivative of tuberculin and lipoprotein are conserved.

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Cite This Study

Coutinho et al. (1977) studied this question.

synapsesocial.com/papers/6a1ab2a88198c9a8aa460194 https://doi.org/10.1002/eji.1830070517