In adults at high cardiovascular risk, low educational level was not significantly associated with the primary composite cardiovascular endpoint (HR 1.16), although it was associated with an increased risk of stroke.
Cohort (n=7,263)
Sí
Do psychosocial factors increase the risk of cardiovascular events in high-risk adults without prior CVD?
Low educational attainment is associated with an increased risk of stroke in high-risk adults without prior CVD, whereas depression and low social support did not show significant associations with CVD incidence.
Estimación del efecto: HR 1.16 (95% CI 0.85-1.57)
Tasa de eventos absoluta: 9.2% vs 7.9%
valor p: p=0.351
BACKGROUND: Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population. METHODS: Longitudinal prospective study of 7263 patients (57.5% women), mean age 67.0 (SD 6.2) free from CVD but at high risk, with a median follow-up of 4.8 years (from October 2003 to December 2010). The Hazard Ratios (HRs) of cardiovascular events (myocardial infarction, stroke, and death from cardiovascular causes) related to educational attainment, diagnosed depression (based on medical records), and low social support (number of people living in the household) were estimated by multivariate Cox regression models. RESULTS: Stroke incidence was associated with low educational level in the whole population (HR: 1.83, 95% CI: 1.09-3.09), and especially in men (HR: 2.11, 95% CI 1.09-4.06). Myocardial infarction and CVD mortality were not associated with any of the psychosocial factors considered. CONCLUSION: Adults with low educational level had a higher risk of stroke. Depression and low social support were not associated with CVD incidence. TRIAL REGISTRATION: Clinical trial registration information unique identifier: ISRCTN35739639.
Mejía-Lancheros et al. (Fri,) conducted a cohort in High cardiovascular risk (n=7,263). Low educational level vs. High educational level was evaluated on Composite of cardiovascular death, myocardial infarction, or stroke (HR 1.16, 95% CI 0.85-1.57, p=0.351). In adults at high cardiovascular risk, low educational level was not significantly associated with the primary composite cardiovascular endpoint (HR 1.16), although it was associated with an increased risk of stroke.