September 1, 2000Open Access

Efflux-Mediated Resistance to Fluoroquinolones in Gram-Negative Bacteria

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Resumen

The introduction of the fluoroquinolones (FQs) in the 1980s provided clinicians with a class of broad-spectrum agents applicable to a range of gram-negative infections including urinary tract infections, gastrointestinal infections, respiratory tract infections, sexually transmitted diseases, bone

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Keith Poole (Fri,) studied this question.

synapsesocial.com/papers/6a1bd3fdb33628da419ceb66 https://doi.org/https://doi.org/10.1128/aac.44.9.2233-2241.2000

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3Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon1993 · 685 citations
4The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump1997 · 143 citations
5Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa1992 · 52 citations

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