June 1, 1980

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

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Resumen

The rat brain capillary permeability coefficient was determined for 27 compounds. The relationship of permeability to octanol/water partition coefficient and molecular weight was found to be predictable for drugs with molecular weights less than 400.

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Cite This Study

Victor A. Levin (Sun,) studied this question.

synapsesocial.com/papers/6a1c2c8169a4af5b15a96c8f https://doi.org/https://doi.org/10.1021/jm00180a022

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