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April 16, 2010Open Access

Development of Rational Drug Combinations with Investigational Targeted Agents

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This manuscript explores specific examples and criteria in which an alternative regulatory process to the existing combination rule would be appropriate and feasible and thus could be adopted by developers.

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Development of Rational Drug Combinations with Investigational Targeted Agents | Synapse

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Clark et al. (Fri,) studied this question.

synapsesocial.com/papers/6a1d271b73c56dd1bd2f4715 https://doi.org/https://doi.org/10.1634/theoncologist.2009-0262