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New representations of thought -- written language, mathematical notation, information graphics, etc -- have been responsible for some of the most significant leaps in the progress of civilization, by expanding humanity's collectively-thinkable territory. But at debilitating cost. These representations, having been invented for static media such as paper, tap into a small subset of human capabilities and neglect the rest. Knowledge work means sitting at a desk, interpreting and manipulating symbols. The human body is reduced to an eye staring at tiny rectangles and fingers on a pen or keyboard. Like any severely unbalanced way of living, this is crippling to mind and body. But less obviously, and more importantly, it is enormously wasteful of the vast human potential. Human beings naturally have many powerful modes of thinking and understanding. Most are incompatible with static media. In a culture that has contorted itself around the limitations of marks on paper, these modes are undeveloped, unrecognized, or scorned.
Bret Victor (Wed,) studied this question.