Abstract As a global public health challenge, food allergy affects hundreds of millions of individuals worldwide. This review provides a recent advance in the field of food allergy, including developments in diagnostic techniques, allergy evaluation methods, and management strategies. In addition, the modulation of food allergies by natural active substances in foods is also emphasized. Combining bioinformatics diagnostics with regulation of dietary actives holds great promise for allergy prevention. Furthermore, evaluation methods that combine dynamic gastrointestinal digestion modeling with bioinformatics provides new ideas for revealing the structural stability of allergens. Finally, enhanced food allergy management has further improved the effectiveness of allergy prevention. This review provides a better understanding and novel insights into the prevention and control of food allergies, as well as explores the potential applications of natural bioactive substances in food allergy management strategies.
Dong et al. (Mon,) studied this question.