Coronary Blood Flow Measured by I 131 lodo-antipyrine

The use of I 131 antipyrine for determining coronary blood flow in intact dogs is described. The correlation with the simultaneous nitrous oxide method was 0.91 ω m 0.22. Partition coefficient and tissue equilibration were directly determined (1.04 ω 0.13). The method as applied requires only two minutes of sampling and is adaptable to direct writing methods.