November 7, 1975

Guanidinium-CsCl Density Gradients for Isopycnic Analysis of Nucleic Acids

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Resumen

The addition of guanidinium chloride to CsCl gradients lowers the apparent density of RNA, DNA, and hybrid polymers in such a way that all three can be banded, fractionated, and analyzed in one gradient with essentially no damage to their chemical integrity or to their biological activity.

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Cite This Study

Enea et al. (Fri,) studied this question.

synapsesocial.com/papers/6a1ea431edce398519af1903 https://doi.org/https://doi.org/10.1126/science.1188358

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5The evaluation of standard sedimentation coefficients of sodium RNA and sodium DNA from sedimentation velocity data in concentrated NaCl and CsCl solutions1965 · 173 citations

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