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The convenience of the galvanic skin response (GSR) and basal skin resistance (R) as indicators of autonomic activity has led to their widespread application in psychological and pharmacological investigations since the late 19th century, but the many fundamental controversies to be found in the literature testify to the questionable reliability of these measures.1-4They can nevertheless furnish dependable information about the level of sympathetic activity provided the various factors outside the nervous system which affect them are adequately controlled. These factors include skin temperature, current density, electrode composition and size, contact medium, and electronic circuitry as well as a miscellaneous group of variables.1,5-13To help establish the requirements for insuring reproducible measurements, we have systematically studied some of these variables and have examined the findings against the background of existing literature. Some material reported elsewhere has been summarized here in the interest of
Robert Edelberg (Sat,) studied this question.