Higher body mass index was associated with increased blood pressure, with each 1 kg/m2 increase in BMI linked to a 0.89 mmHg higher 24-hour systolic blood pressure (95% CI 0.87-0.91).
Observational (n=65,894)
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Is higher body mass index associated with elevated ambulatory blood pressure parameters?
In a large Hungarian registry, higher BMI was significantly associated with elevated 24-hour ambulatory blood pressure and a higher prevalence of non-dipping and reverse dipping patterns.
Mean Difference: 0.89 (95% CI 0.87–0.91)
Objective: The aim of this study was to analyze data in the ambulatory blood pressure monitoring (ABPM) registry by the Hungarian Society of Hypertension, to assess the associations between nutritional status and blood pressure (BP) and BP-related parameters. Design and method: ABPM data from 65,894 patients collected between 2021 and 2025 were analyzed. The mean age was 56±15.1 years. The body mass index (BMI) was 28.8±5.3 kg/m2. 45.4% were men and 54.6% were women, with BMI of 29.3±4.9 and 28.3±5.5 kg/m2, respectively. All analyses were performed in Python using pandas, numpy and statsmodels libraries. Results: In the total population, only 24.6% of participants were of normal weight, 39% were overweight (OW) and 36.4% were obese. The proportion of OW and obese patients was significantly higher in men compared with women (42.4% vs. 36.1% and 39.6% vs. 33.8% both p<0.001). Significantly higher 24-hour systolic and diastolic blood pressure (SBP and DBP) values were observed in OW and obese patients compared with those of normal weight (132.3±12.7 and 138.4±14.9 vs. 127.6±12.6 mmHg for SBP, and 78.6±9.8 and 80.9±10.3 vs. 76.4±9.7 mmHg for DBP, respectively). Similar differences were observed in the daytime and nighttime SBP and DBP values across the different nutritional status groups. Regarding diurnal index (DI), the proportion of non-dippers were higher in OW and obese patients compared with normal weight individuals (41.3% and 42.6% vs 40%). The prevalence of reverse dipper was 8,8% both in normal and OW individuals, while we observed a much higher frequency (10.7%) in obese patients. The association between BMI and 24-hour SBP remained significant after adjustment for demographics, comorbidities, lifestyle factors and antihypertensive treatment. Each 1 kg/m2 increase in BMI was associated with a 0.89 0.87-0.91 mmHg higher 24-hour SBP and a 0.32 0.31-0.34 mmHg higher 24-hour DBP, with comparable associations for daytime and nighttime BP. Conclusions: Data from this large Hungarian population underscore the significant association between nutritional status and blood pressure. These results emphasize the importance of addressing overweight and obesity in hypertension management.
Székely et al. (Fri,) conducted a observational in Hypertension (n=65,894). Higher body mass index (BMI) vs. Lower BMI was evaluated on 24-hour systolic blood pressure (MD 0.89, 95% CI 0.87-0.91). Higher body mass index was associated with increased blood pressure, with each 1 kg/m2 increase in BMI linked to a 0.89 mmHg higher 24-hour systolic blood pressure (95% CI 0.87-0.91).