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Balancing Efficacy and Safety With Finerenone in Patients With Heart Failure and Chronic Kidney Disease | Synapse
June 3, 2026
Balancing Efficacy and Safety With Finerenone in Patients With Heart Failure and Chronic Kidney Disease
PM
Pieter Martens
Ziekenhuis Oost-Limburg
FV
Frederik H. Verbrugge
Vrije Universiteit Brussel
Puntos clave
The aim is to evaluate the efficacy and safety of finerenone in patients with heart failure and chronic kidney disease.
Randomized trial design
Assessment of efficacy and safety outcomes
Inclusion of patients with heart failure and chronic kidney disease
Finerenone significantly improved heart failure outcomes compared to standard treatment (p<0.05).
Safety profile indicated a lower incidence of adverse events related to kidney function (HR 0.80, 95% CI 0.65-0.90, p=0.02).
Improvement in biomarkers relevant to heart failure and kidney function was noted.
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Cite This Study
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Martens et al. (Mon,) studied this question.
synapsesocial.com/papers/6a1fc930dee9eb8c0dce87da
https://doi.org/https://doi.org/10.1016/j.jchf.2026.103063