Prediction of quality of life in patients with end‐stage renal disease

Objectives. To examine the relationship between dialysis adequacy, psychological status and quality of life in patients with end‐stage renal disease (ESRD) treated with continuous ambulatory peritoneal dialysis (CAPD). Design. A single group, cross‐sectional study with correlational and multiple regression analyses. Methods. Seventy‐two patients were assessed on measures of dialysis adequacy (kinetic transfer/volume urea), self‐report depression and anxiety (Hospital Anxiety and Depression (HAD) scale), locus of control (Locus of Control of Behaviour (LCB) scale) and quality of life (Kidney Disease Quality of Life (KDQOL) instrument). Results. Using correlational and multiple regression analyses it was found that psychological factors, particularly depression, were much stronger determinants of quality of life in CAPD patients than biological indices of dialysis adequacy. A significant proportion of the patients was distressed as assessed by the HAD scale. Patients also tended to be external in locus of control orientation. Conclusions. Assessment of psychological status and psychosocial needs should be an integral part of the therapy offered to CAPD patients in order for them to achieve an optimal quality of life.