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ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTTherapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain BarrierSilke Krol*†, Richard Macrez‡§, Fabian Docagne‡, Gilles Defer‡§, Sophie Laurent∥, Masoud Rahman⊥, Mohammad J. Hajipour⊥, Patrick G. Kehoe*∇, and Morteza Mahmoudi*⊥▲#View Author Information† Fondazione IRCCS Institute of Neurology "Carlo Besta", Milan, Italy‡ Inserm U919, University Caen Basse Normandie, Serine Proteases and Pathophysiology of the Neurovascular Unit, GIP CYCERON, F-14074 Caen, France§ Department of Neurology, University Hospital of Caen, Caen, France∥ Department of General, Organic, and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Avenue Maistriau, 19, B-7000 Mons, Belgium⊥ Laboratory of NanoBio Interactions (www.biospion.com), Department of Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran∇ Dementia Research Group, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, John James Laboratories, Frenchay Hospital, Bristol, U.K.▲ Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran# Current address: School of Chemical Sciences, University of Illinois at Urbana−Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States*S.K.: e-mail, email protected. P.K.: e-mail, email protected. M.M.: Web, www.biospion.com; e-mail, email protectedCite this: Chem. Rev. 2013, 113, 3, 1877–1903Publication Date (Web):November 19, 2012Publication History Received18 December 2011Published online19 November 2012Published inissue 13 March 2013https://pubs.acs.org/doi/10.1021/cr200472ghttps://doi.org/10.1021/cr200472greview-articleACS PublicationsCopyright © 2012 American Chemical SocietyRequest reuse permissionsArticle Views6711Altmetric-Citations171LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Cells,Central nervous system,Drug delivery,Molecules,Peptides and proteins Get e-Alerts
Krol et al. (Mon,) studied this question.