Systolic blood pressure was negatively associated with prevalent atrial fibrillation (OR per 10-mm Hg increase 0.79; 95% CI 0.71-0.88; P<0.0001) in an elderly Chinese population.
Cross-Sectional (n=6,966)
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Is blood pressure status associated with prevalent atrial fibrillation in an elderly Chinese population?
In an elderly Chinese population, the relationship between blood pressure and prevalent atrial fibrillation is U-shaped, with the lowest risk at high-normal blood pressure.
Odds Ratio: 0.79 (95% CI 0.71–0.88)
valor p: p=<0.0001
Abstract OBJECTIVE Atrial fibrillation (AF) and hypertension are prevalent chronic disease conditions in the elderly population. In the present cross-sectional study, we investigated the association between blood pressure (BP) and AF in an elderly Chinese population. METHOD Our elderly (≥65 years) subjects were residents recruited from 6 communities in Shanghai from 2006 to 2017. Atrial fibrillation was systematically screened by rest 12-lead electrocardiogram (ECG) or by a handheld single-lead ECG. BP status was defined according to the European hypertension guidelines as optimal, normal, or high-normal BP, and stage 1, 2, or 3 hypertension. RESULT In the 6,966 participants (women 56.0%, mean age: 72.3 years), the prevalence of AF was 3.3%, and the prevalence of hypertension was 58.7% (83.7% treated). In all participants, the association with prevalent AF was negative for systolic BP (odds ratio OR per 10-mm Hg increase 0.79, 95% confidence interval CI: 0.71–0.88, P 0.0001) but positive for diastolic BP (OR per 5-mm Hg increase 1.11, 95% CI: 1.02–1.22, P = 0.02). In untreated participants (n = 3,544), the association with prevalent AF was U-shaped for both systolic and diastolic BP, with the nadir at high-normal BP and a significantly higher risk of prevalent AF in optimal systolic BP (OR: 3.11, 95% CI: 1.65–5.85, P = 0.004) and stage 2 or 3 diastolic hypertension relative to the nadir (OR: 8.04, 95% CI: 2.28–28.3, P = 0.001). CONCLUSION In the elderly population, BP shows a complicated relationship with prevalent AF, with high-normal BP at the lowest risk and optimal systolic BP and stage 2 or 3 diastolic hypertension at increased risks.
Chen et al. (Fri,) conducted a cross-sectional in Atrial fibrillation and hypertension (n=6,966). Blood pressure status vs. Per unit increase or high-normal blood pressure was evaluated on Prevalent atrial fibrillation (OR 0.79, 95% CI 0.71-0.88, p=<0.0001). Systolic blood pressure was negatively associated with prevalent atrial fibrillation (OR per 10-mm Hg increase 0.79; 95% CI 0.71-0.88; P<0.0001) in an elderly Chinese population.