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For many years, the relationship between obesity and heart disease and hypertension has presented a challenging problem. The physiological effects of obesity on the normal heart and its harmful influences on the diseased heart are well established. 1 Statistics compiled by insurance companies have shown conclusively that overweight alone is injurious and shortens life. 2 In middle and later life the lowest mortality ratios were observed in those whose weight was below the average for age. 3 There is overwhelming evidence, also, that obese persons have a much higher mortality rate from heart disease than those of average or lower weight. The difference has been as high as 60% for men who are 25% or more overweight. 4 There have been few clinical studies on a possible etiological relationship between obesity and coronary disease and hypertension, and the results reported have been conflicting. The problem of the relationship of obesity
Arthur M. Mastér (Sat,) studied this question.