January 1, 1981Open Access

Replicating, differentiated macrophages can serve as in vitro targets for transformation by avian myeloblastosis virus

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Resumen

Pure cultures of chicken macrophages were characterized functionally and transformed by avian myeloblastosis virus. Transformed cells exhibited an altered function. The efficiency of transformation was limited by the mitotic activity of the macrophages.

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Durban et al. (Thu,) studied this question.

synapsesocial.com/papers/6a208c68de5eb88fb8301edc https://doi.org/https://doi.org/10.1128/jvi.37.1.488-492.1981

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Virus of Avian Myeloblastosis. XIV. Neoplastic Response of Normal Chicken Bone Marrow Treated with the Virus in Tissue Culture2<xref ref-type="fn" rid="FN1">2</xref>1960 · 42 citations
2Light Inactivation of Focus Formation by Chicken Embryo Fibroblasts infected with Avian Sarcoma Virus in the Presence of 5-Bromodeoxyuridine1970 · 73 citations
3Properties of Cells Infected with Avian Myeloblastosis Virus1962 · 46 citations
4A Quantitative Assay for Avian Myeloblastosis Virus.1967 · 20 citations
5Cell transformation induced by Rous sarcoma virus: analysis of density dependence.1971 · 17 citations

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