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July 14, 1960New England Journal of Medicine70 citations

Bacterial Endocarditis Following Surgery for Congenital Heart Disease

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LLLeonard M. LindeHHHenry L. Heins

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P
Population
Patients with congenital heart disease who develop bacterial endocarditis following corrective heart surgery

The clinical presentation of bacterial endocarditis in the early postoperative period following congenital heart surgery differs from the classic picture seen in unoperated patients.

Abstract

BEFORE the antibiotic era subacute bacterial endocarditis was almost invariably a fatal complication in congenital and acquired heart disease.1 2 3 The offending organism was Streptococcus viridans in 85 to 95 per cent of cases in several large series.1 2 3 4 5 6 7 With the advent of antibiotic therapy the incidence and mortality of bacterial endocarditis progressively decreased,5 , 8 , 9 but other, more resistant organisms, particularly the Staphylococcus, assumed etiologic significance.8 , 12 Further changes in the clinical picture of endocarditis were next seen with the advent of corrective heart surgery.The classic clinical picture of bacterial endocarditis is not seen with infection in the early postoperative period. Altered host . . .

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Cite This Study

Linde et al. (1960) studied this question.

synapsesocial.com/papers/6a20a752b48790a83591d7e5https://doi.org/10.1056/nejm196007142630203
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