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Noncycling Tumor Cells: Mitogenic Response to Antilymphocytic Serum | Synapse

November 8, 1968

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Noncycling Tumor Cells: Mitogenic Response to Antilymphocytic Serum

JDJerome J. DeCosseMemorial Hospital of South Bend SGSeymour GelfantMarine Biological Laboratory

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Resumen

After continuous labeling with tritiated thymidine for a period several times the cell generation time, some ELD ascites cells remained unlabeled. Despite continued exposure to tritiated thymidine, unlabeled mitoses appeared promptly after administration of mouse antilymphocytic serum. Immunosuppression released some noncycling G(2) tumor cells into mitosis.

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Cite This Study

DeCosse et al. (Fri,) studied this question.

synapsesocial.com/papers/6a2115cd38e3bbbbff02b5db https://doi.org/https://doi.org/10.1126/science.162.3854.698