Abstract Purpose Nutritional status and dietary antioxidant capacity are important determinants of clinical resilience in cancer; however, data in hematological malignancies remain limited. We aimed to compare nutritional status, dietary total antioxidant capacity (DTAC), and dietary diversity between patients with newly diagnosed hematological malignancies and healthy controls. Methods This case–control study included 34 patients with newly diagnosed hematological malignancies (12 lymphoma, 11 leukaemia, 11 multiple myeloma) and 34 age- and sex-matched healthy controls aged 18–65 years. DTAC was estimated using the ferric reducing antioxidant power (FRAP) method based on a validated food frequency questionnaire. Nutrient intakes and the dietary diversity score (DDS) were derived from 3-day dietary records. Nutritional status was assessed using the Global Leadership Initiative on Malnutrition (GLIM) criteria, along with fat-free mass index (FFMI), and mid-upper arm circumference (MUAC). Results Patients had significantly lower DTAC levels than controls (3.85 ± 1.58 vs. 8.68 ± 3.21 mmol/day, p 0.05). DTAC was positively correlated with intakes of coffee, whole-grain bread, green vegetables, citrus fruits, and fresh fruit ( p ≤ 0.05). Conclusions Significant differences in nutritional status and DTAC between patients and healthy individuals suggest that suboptimal dietary patterns may accompany hematological malignancies at diagnosis. These findings highlight the potential importance of adequate macro- and micronutrient intake; however, further prospective studies are needed to determine whether targeted nutritional interventions can improve clinical outcomes or contribute to long-term risk reduction.
Koyuncu et al. (Mon,) studied this question.
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