Visible-light-mediated propargylation of phenols/thiophenols via organic photocatalysis

Puntos clave

• The aim is to develop a direct method for the alkynylation of anisoles and thioanisoles using visible light without transition metals.
• Implemented a transition-metal-free protocol for alkynylation
• Utilized visible light and organic photocatalysis
• Explored a range of substrates and gram-scale applications.
• Successfully achieved direct dehydrogenative alkynylation with a broad substrate range
• Demonstrated scalability for gram-scale production
• Unveiled a well-elucidated non-radical chain mechanism.