Triglycerides and hypertriglyceridemic very-low-density lipoproteins are important risk factors for premature coronary artery disease and may be involved in atherogenesis and thrombogenesis.
A recent review of epidemiological studies indicate that triglycerides are an important risk factor for premature coronary artery disease and/or myocardial infarction. Triglyceride-rich lipoproteins that accumulate in hypertriglyceridemic subjects may be involved both in atherogenesis and in thrombogenesis. Studies published in the last year confirm and extend earlier observations that hypertriglyceridemic very-low-density lipoproteins are abnormal and potentially atherogenic or thrombogenic due to abnormal receptor-mediated interactions with fibroblasts, macrophages or endothelial cells.
Gianturco et al. (Tue,) conducted a review in Premature coronary artery disease and myocardial infarction. Triglyceride-rich lipoproteins was evaluated on Atherogenesis and thrombogenesis. Triglycerides and hypertriglyceridemic very-low-density lipoproteins are important risk factors for premature coronary artery disease and may be involved in atherogenesis and thrombogenesis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: