Does vasoactive intestinal peptide improve inotropic and pulmonary vasodilatory effects in monocrotaline-induced pulmonary hypertensive rabbits following cardiopulmonary bypass compared to isoproterenol and nitroglycerine?
Vasoactive intestinal peptide demonstrates dose-responsive positive inotropic and pulmonary vasodilatory effects in a rabbit model of pulmonary hypertension following cardiopulmonary bypass.
VIP has dose responsive, positive inotropic and pulmonary vasodilatory effects in whole body CPB model acting via calcium channels.
Serdar Günaydın (Mon,) studied this question.