Specific Binding of Concanavalin A to Cross-Linked Dextran Gels

Concanavalin A, a globulin found in the jack bean, agglutinates certain animal erythrocytes (Sumner Cifonelli, Montgomery Goldstein, Hollerman & Merrick, 1963,1965a). The interaction of concanavalin A with carbohydrates is very specific, formation of a visible precipitate occurring only with branched polysaccharides that contain CX-D-glucopyranosyl or x-D-mannopyranosyl resi- dues at non-reducing chain ends (Goldstein et al.