Hypertension reduced early diastolic left atrial longitudinal strain compared to controls (14.9% vs 22.1%, P<0.001), with further impairment seen in patients with coexisting diabetes (12.3%, P<0.05).
Observational (n=190)
Does coexisting diabetes further impair left atrial phasic function assessed by 2DSTE in patients with hypertension?
2D speckle tracking echocardiography demonstrates that hypertension impairs left atrial reservoir and conduit functions, which are further worsened by coexisting diabetes.
Tasa de eventos absoluta: 14.9% vs 22.1%
valor p: p=<0.001
OBJECTIVE: To evaluate the left atrial phasic function of hypertensive patients with or without coexisting diabetes using two-dimensional speckle tracking echocardiography (2DSTE)-based strain and strain rate imaging and volumetric parameters. METHODS: The study included an isolated hypertension group (HT group) comprising 99 patients, a hypertension and diabetes group (HT + DM group) comprising 65 patients, and 26 age-matched healthy controls. The 2DSTE-based strain and strain rate images were studied, and the following parameters were measured: peak left atrial longitudinal strain (LAS-S ), early diastolic (LAS-E ) and late diastolic (LAS-A ) atrial longitudinal strains, and systolic (LASR-S ), early diastolic (LASR-E ) and late diastolic (LASR-A ) strain rates. RESULTS: The LAS-S and LASR-S were lower in the HT group and the HT + DM group compared with the control group (P 0.05). Multivariate regression analysis revealed that HT and DM were independently related to LAS-E and LASR-E . CONCLUSIONS: Hypertension can lead to abnormal left atrial reservoir and conduit functions, and coexisting diabetes can further impair conduit function. 2DSTE-derived strain and strain rate imaging are sensitive methods for evaluating left atrial phasic function.
Liu et al. (Fri,) conducted a observational in Hypertension and diabetes (n=190). Hypertension with or without diabetes vs. Healthy controls was evaluated on Early diastolic left atrial longitudinal strain (LAS-E) (p=<0.001). Hypertension reduced early diastolic left atrial longitudinal strain compared to controls (14.9% vs 22.1%, P<0.001), with further impairment seen in patients with coexisting diabetes (12.3%, P<0.05).