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March 1, 1998Nephrology Dialysis TransplantationOpen Access

The effects of exercise training on muscle atrophy in haemodialysis patients

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Authors

EKEvangelia KouidiMAMaria AlbaniKNKonstantinos Natsis

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Overview

Randomized trial evaluates exercise training effects on muscle atrophy in haemodialysis patients, suggesting significant improvements.

Key Points

  • To assess the impact of exercise training on muscle atrophy and related functional capacity in haemodialysis patients.
  • Seven haemodialysis patients underwent a 6-month exercise rehabilitation programme.
  • Open muscle biopsies were performed before and after the rehabilitation to assess muscle fibre changes and ultrastructural alterations.
  • Measurements included exercise capacity, muscle strength, and neurophysiological testing pre- and post-training.
  • Muscle atrophy was significant, with a mean muscle fibre area of 2548 microm2 before training.
  • Exercise training resulted in a 51% increase in type II fibres and a 29% increase in muscle fibre area post-training.
  • Patients showed a 48% increase in VO2 peak and improved peak muscle strength and nerve conduction velocity.

Cite This Study

Kouidi et al. (1998) studied this question.

synapsesocial.com/papers/6a2202241451ae9ed3e22734https://doi.org/10.1093/ndt/13.3.685
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