This early clinicopathologic study describes cerebral vasothrombosis as a potential underlying pathology for cerebral manifestations in patients with heart failure.
Article1 January 1955CEREBRAL VASOTHROMBOSIS IN CARDIAC DISEASES: CLINICOPATHOLOGIC STUDYI. M. SCHEINKER, M.D.I. M. SCHEINKER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-42-1-128 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCerebral manifestations in acute and chronic heart failure are not uncommon. The underlying pathology may consist of widespread areas of softening disseminated throughout one or both hemispheres. Hemiplegias, aphasias and other clinical syndromes have been observed during or following an acute phase of cardiac failure.1The purpose of this presentation is to call attention to the frequent occurrence of thrombotic occlusion of small cerebral veins in cases of chronic heart failure. The vascular alteration described as "cerebral vasothrombosis"2is characterized by thrombotic occlusion of extremely distended and congested small veins. The thrombi are composed of curved strands of fibrin mixed...Bibliography1. Scheinker IM: Medical neuropathology, 1952, Charles C. Thomas, Springfield, Illinois, pp. 3-58. Google Scholar2. Scheinker IM: Vasothrombosis of the central nervous system, Arch. Neurol. and Psychiat. 53: 171, 1945. CrossrefGoogle Scholar3. EckerDeren ADM: Apoplexy apparently precipitated by low blood pressure, Am. J. M. Sc. 201: 415, 1941. CrossrefGoogle Scholar4. WolfSiris AJ: Acute non-traumatic encephalomalacia complicating neurosurgical operations in the sitting position, Bull. Neurol. Inst. New York 6: 42, 1937. Google Scholar5. Lewis N: Psychic phenomena in association with cardiac failure, Arch. Neurol. and Psychiat. 37: 782, 1937. CrossrefGoogle Scholar6. Wortis J: Cardiac psychosis and the symptoms of anxiety, Am. Heart J. 13: 394-412, 1937. CrossrefGoogle Scholar7. HarveyFinch WPCA: Dicumarol prophylaxis of thromboembolic disease in congestive heart failure, New England J. Med. 242: 208-211 (Feb. 9) 1950. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication June 1, 1954.From the Department of Neurology and Neurosurgery, New York Medical College, Flower and Fifth Avenue Hospitals.†Deceased. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySPONTANEOUS CEREBRAL HAEMORRHAGE AND ENCEPHALOMALACIA. A Clinico-Pathological Study of 263 Cases with Special Reference to Cardiovascular Diseases and Cerebral AtherosclerosisThe Treatment of Cerebrovascular AccidentRecent Advances in the Investigation and Management of Cerebrovascular Disease 1 January 1955Volume 42, Issue 1Page: 128-135KeywordsFibrinHeart diseasesHeart failureNeurologyNeurosurgeryVeins ePublished: 1 December 2008 Issue Published: 1 January 1955 PDF downloadLoading ...
I. MARK SCHEINKER (Sat,) studied this question.
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