Higher health-related quality of life was significantly associated with lower day-to-day systolic blood pressure variability (r = -0.45, p < 0.001) in patients with mild hypertension.
Observational (n=56)
Non-randomized
Sí
56 adults (mean age 64 years) with mild or pre-hypertension, followed for 8 weeks to assess the relationship between day-to-day blood pressure variability and quality of life.
Quality of Life (QOL)
Correlation between total Quality of Life (QOL) score and day-to-day systolic blood pressure variability (standard deviation of SBP) at 8 weeks — r = -0.45, p=<0.001
Estimación del efecto: r = -0.45
valor p: p=<0.001
PURPOSE: Blood pressure variability (BPV) is emerging as an important cardiovascular prognostic factor in addition to average blood pressure level. While there have been some suggestions for the determinants of the blood pressure variability, little is known about the relationship between the blood pressure variability and health-related quality of life (QOL). MATERIALS AND METHODS: Fifty-six men and women with mild hypertension were enrolled from local health centers in Republic of Korea, from April to October 2009. They self-monitored their blood pressure twice daily for 8 weeks. Pharmacological treatment was not changed during the period. Standard deviation and coefficient of variation of blood pressure measurements were calculated as indices of BPV. Measurements of QOL were done at initial and at 8-week follow-up visits. RESULTS: Study subjects had gender ratio of 39:41 (male:female) and the mean age was 64±10 years. The mean home blood pressure's at week 4 and 8 did not differ from baseline. Total score of QOL at follow-up visit and change of QOL among two measurements were negatively correlated to BPV indices, i.e., higher QOL was associated with lower BPV. This finding persisted after adjustment for age, gender and the number of antihypertensive agents. Among dimensions of QOL, physical, mental and hypertension-related dimensions were associated particularly with BPV. CONCLUSION: QOL may be a significant determinant of BPV. Improvement of QOL may lead to favorable changes in BPV.
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Sung et al. (Wed,) conducted a observational in Mild hypertension or pre-hypertension (n=56). Quality of Life (QOL) was evaluated on Correlation between total Quality of Life (QOL) score and day-to-day systolic blood pressure variability (standard deviation of SBP) at 8 weeks (r = -0.45, p=<0.001). Higher health-related quality of life was significantly associated with lower day-to-day systolic blood pressure variability (r = -0.45, p < 0.001) in patients with mild hypertension.
synapsesocial.com/papers/6a229e8d54bc213887d2b877 — DOI: https://doi.org/10.3349/ymj.2014.55.2.374
Jidong Sung
Preventive Cardiology
Jong‐Min Woo
Rutgers, The State University of New Jersey
Won Bae Kim
Ulsan College
Yonsei Medical Journal
Sungkyunkwan University
Samsung Medical Center
Inje University
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