Changes in the Composition of the Urine After Muscular Exercise

The effect of short periods of strenuous exercise on the composition of the urine was studied. The urine from normal men was collected in ten minute periods and after a suitable fore-period stair running for one or two minutes was introduced and the collections of urine continued. It was hoped in this way to learn the rapidity and the extent of the response of the kidney to the chemical and physical changes taking place in the organism. There was a marked fall in the urine volume after exercise which could not be overcome by drinking small quantities of water at frequent intervals. A considerable increase in the excretion of acids and conservation of base were demonstrated by the rapid increase in the hydrogen ion concentration, titrat-able acidity, ammonia and ratio of ammonia to total nitrogen of the urine. The inorganic phosphates increased parallel with the acid excretion. The values reached a maximum in twenty minutes and returned to normal in less than an hour. The hydrogen ion concentration frequen...