(149) Penile Prosthesis Implantation Leads to Substantial Long-Term Satisfaction Improvement in Low-Scoring Patients and Partners: Implications for Counselling (PHOENIX Registry)

Abstract Introduction Penile prosthesis implantation (PPI) is an established treatment for therapy-resistant erectile dysfunction (ED). The modified Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) questionnaire assesses treatment satisfaction among both patients and their partners. Early postoperative follow-up may show only modest improvement in some cases, highlighting the need for long-term data to better characterize the trajectory of treatment outcomes. Objective To assess the change in EDITS scores between 12 weeks and 1-year post-PPI in the PHOENIX registry cohort, with particular focus on patients and partners presenting with low (≤50) initial scores. Methods A paired analysis was performed on individuals who completed EDITS questionnaire at both 12 weeks and 1-year post-PPI. In total, EDITS data from 913 patients and 290 partners were available, with respectively 619 and 175 providing complete data at both time points. A subgroup analysis was performed on 62 patients and 19 partners with EDITS ≤50 at 12 weeks. Results In the overall cohort, mean patient EDITS scores increased significantly from 80.3 at 12 weeks to 84.1 at 1 year. Normality of difference scores was confirmed in the patient group (p = 0.083) and the partner subgroup (p = 0.726). Among individuals with an EDITS score ≤50 at 12 weeks, both patients and partners demonstrated marked and highly significant improvements after one year. Patients (n = 62) improved from a mean of 33.5 by 34.8 points (95% CI: 27.0–42.5; t = 8.98, p 0.001 1×10-¹2), while partners (n = 19) mean score of 30.3 improved by 48.2 points (95% CI: 38.4–57.9; t = 10.35, p 0.001). Conclusions While the overall PPI cohort reported high early satisfaction, this analysis reveals that both patients and partners starting with the lowest EDITS achieve a substantial improvement by one year. These findings provide strong support for preoperative counselling, reassuring couples that major improvement continues over the long term. Nevertheless, final scores in the EDITS≤50 group remained below those of the overall cohort at 12 weeks, suggesting that further follow-up is warranted to explore whether continued normalization occurs over time. Disclosure Yes, this is sponsored by industry/sponsor: Boston Scientific Corporation United States and Coloplast A/S Denmark Clarification: Industry funding only - investigator initiated and executed study