Coronary artery calcium scoring improves cardiovascular risk prediction beyond traditional calculators, particularly benefiting asymptomatic individuals at intermediate risk to guide preventive pharmacotherapy.
Does coronary artery calcium scoring improve cardiovascular risk stratification in asymptomatic individuals?
Coronary artery calcium scoring is a valuable non-invasive imaging tool for refining cardiovascular risk stratification and guiding preventive pharmacotherapy, especially in intermediate-risk asymptomatic individuals.
BACKGROUND: Identifying high-risk asymptomatic individuals remains the cornerstone of cardiovascular disease prevention. Coronary artery calcium is a highly specific marker of atherosclerosis that can be quantified using non-contrast computed tomography. The resulting calcium score has the capacity to improve current methods of risk stratification. OBJECTIVE: The aim of this article is to provide an overview of calcium scoring, including its method of acquisition, indications, interpretation and role in prognostication. DISCUSSION: Calcium score has been shown to convincingly predict future cardiovascular risk in the asymptomatic population across a wide range of ethnicities, ages and sexes. Individuals at intermediate Framingham risk benefit the most from calcium scoring, which can be used to inform the need for preventive pharmacotherapy. Calcium scoring can be repeated after five years to reassess cardiovascular risk, especially when there is a decision to defer statin therapy on the basis of absence of coronary calcium.
Chua et al. (Sat,) conducted a review in Coronary artery disease. Coronary artery calcium scoring vs. Traditional risk calculators was evaluated. Coronary artery calcium scoring improves cardiovascular risk prediction beyond traditional calculators, particularly benefiting asymptomatic individuals at intermediate risk to guide preventive pharmacotherapy.
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