November 16, 2004

Recent Insights into the Structure and Mechanism of the Sodium Pump

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Resumen

The sodium pump (or Na-K-ATPase) is essential to the function of animal cells. Publication of the related calcium pump (SERCA) structure together with several recent results from a variety of approaches allow us to propose a mechanistic model to answer the question: "How does the sodium pump pump?"

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Cite This Study

J. D. Horisberger (Tue,) studied this question.

synapsesocial.com/papers/6a3215e4892369be8eddb44c https://doi.org/https://doi.org/10.1152/physiol.00013.2004

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1H+/ATP stoichiometry for the gastric (K++H+)-ATPase1981 · 68 citations
2Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution2000 · 1,797 citations
3Structural similarities of Na,K-ATPase and SERCA, the Ca2+-ATPase of the sarcoplasmic reticulum2001 · 151 citations
4A channel mechanism for electrogenic ion pumps1979 · 124 citations
5Palytoxin acts through Na+, K+-ATPase1989 · 224 citations

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