Abstract Introduction: Despite being a widely used therapy in urinary incontinence (UI), homeopathy has little and inconsistent research support. Aim: This clinical trial aimed to evaluate the efficacy of individualized homeopathic medicinal products (IHMPs) versus placebo in the treatment of UI in the elderly. Materials and Methods: To determine the differences between identical-looking placebos ( n = 30) and IHMPs ( n = 30) while concomitant care measures were administered to both groups (e.g., drinking restrictions, weight loss for obese people, and pelvic floor muscle exercises), a 6-month, randomized, double-blind, placebo-controlled trial was carried out on sixty elderly people with UI. The International Consultation on Incontinence Questionnaire – UI – Short Form (ICIQ-UI-SF) served as the main outcome measure, whereas the Quality-of-Life Scale served as the secondary measure. The assessments were taken every month for a maximum of 6 months. After calculating the missing values, the intention-to-treat sample was analyzed to detect group differences and effect sizes. Results: There were statistically significant group differences in ICIQ-UI-SF (IHMPs: 6.4 ± 3.0; placebo: 8.7 ± 2.5; mean difference: −2.3, 95% confidence interval −3.7 to −0.9, P = 0.002, d = 0.833). The secondary outcome could not demonstrate any statistical significance, either in the total score ( P = 0.086) or in other subscales, except recreation ( P = 0.002). Twenty-nine different remedies were prescribed: among them, Sulfur , Thuja occidentalis , and Causticum were the most frequently prescribed ones. Conclusions: When compared to placebos, IHMPs showed encouraging effects in the management of UI in older adults. Trial registration: CTRI/2022/04/041931.
Gunin et al. (Thu,) studied this question.