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The present study was conducted to see the effect of pravastatin on lipid composition of newly-secreted VLDL after injection of Triton WR 1339 in rats. Changes in the ration of apolipoprotein (apo) B subspecies in this lipoprotein fraction after pravastatin were also examined in order to determine if there is any relationship between Ch biosynthesis and apoB subspecies metabolism
Yoshino et al. (Mon,) studied this question.