Poor medication adherence (OR 3.87; 95% CI 1.67-8.97; p=0.002) and absence of ACEI/ARB therapy (OR 2.40) were significantly associated with early 30-day readmission in heart failure patients.
Cross-Sectional (n=136)
No
Poor medication adherence and lack of ACEI/ARB therapy are significant predictors of 30-day heart failure readmission in a Tanzanian tertiary hospital.
Odds Ratio: 3.87 (95% CI 1.67–8.97)
valor p: p=0.002
Introduction . Heart failure (HF) is characterized by frequent episodes of decompensation, leading to a high hospitalization burden. More than 50% of index hospitalizations for HF patients return within 6 months of discharge. Once the patient is readmitted, the risk of further disease progression and the mortality rate are increased. A lot of patients are readmitted due to factors such as poor medication adherence, infections, or worsening comorbidities. The aim of our study was to identify the inpatient burden of HF readmission and to identify the factors associated with early readmission. Methods . A hospital-based cross-sectional analytical study was conducted from November 2018 to April 2019 within the medical wards at Kilimanjaro Christian Medical Centre (KCMC), which is a teaching and referral hospital in north-eastern Tanzania. The study population included all patients with HF admitted within the medical ward. Data were collected using questionnaires and blood and radiological investigations, and analysis was done using Statistical Package for Social Science (SPSS) version 25. Chi-square test was used to compare proportions of categorical variables. Logistic regression was used to determine the likelihood for readmission, and p-value of p=0.043), poor medication adherence (OR = 3.87, 95% CI = 1.67–8.97, p=0.002), absence of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) (OR = 2.40, 95% CI = 1.09–5.31, p=0.030), and pleural effusion (OR 3.25, 95% CI = 1.44–7.32, p=0.004). Conclusion . Heart failure is a burden due to a large number of admissions and readmissions. Factors such as poor medication adherence and absence of adequate HF therapy, especially the absence of regimes containing ACEI or ARB, need to be targeted to reduce the number of readmissions. This will help reduce the risk of further decompensations, disease progression, and mortality rate.
Sadiq et al. (Thu,) conducted a cross-sectional in Heart failure (n=136). Poor medication adherence was evaluated on Early readmission within 30 days after discharge (OR 3.87, 95% CI 1.67-8.97, p=0.002). Poor medication adherence (OR 3.87; 95% CI 1.67-8.97; p=0.002) and absence of ACEI/ARB therapy (OR 2.40) were significantly associated with early 30-day readmission in heart failure patients.
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