A 16-week individualized exercise program for fatigued breast cancer patients did not meet its primary feasibility composite outcome, achieving only 30.3% program adherence.
Does a 16-week individualized exercise program embedded in a cardiac rehabilitation program achieve feasibility targets in fatigued breast cancer patients?
Purpose: Exercise is beneficial to quality of life after cancer treatment, yet few cancer survivors meet exercise guidelines. Our study sought to determine the feasibility of an oncology rehabilitation exercise program embedded within a cardiac rehabilitation program. Methods: Patients who rated their fatigue >4/10 after completion of adjuvant chemotherapy for breast cancer were screened for eligibility and the outcomes were assessed (Piper Fatigue Scale, Functional Assessment of Cancer Therapy-Breast FACT-B, Edmonton Symptom Assessment System, body composition, stress test, and physical activity measurement accelerometer). Participants received individualized exercise prescription. Following the 16-week program, repeat assessment plus patient acceptance and satisfaction survey was completed. The primary end point was the composite of accrual rate >25%, program adherence >80%, and mean compliance with accelerometer use >80%. Results: Twenty of 24 screened patients consented to the study and completed the baseline assessment. Adherence was 30.3%. Mean accelerometer use was 3.88/7 days (78%). Fatigue at baseline was rated at 4.82/10, and at 3.59 ( p = 0.09) after the intervention. Overall well-being (FACT-B) score changed from 92.7 to 98.3 ( p = 0.05). There were no significant changes in body composition (except for bone mineral content), aerobic exercise capacity, or activity patterns. Conclusion: Although the primary outcome was not met, our study indicates that an oncology exercise rehabilitation program can be incorporated into an existing cardiac rehabilitation program. Based on feedback received, we propose that in order to achieve exercise goals, frequent, encouraging, and tailored feedback and group sessions to foster a sense of community may additionally be needed to strengthen adherence to a prescribed exercise program. Keywords: breast cancer rehabilitation, fatigue, exercise, community setting
Jesus et al. (Wed,) conducted a other in Fatigue in breast cancer patients (n=20). Individualized exercise prescription was evaluated on Composite of accrual rate >25%, program adherence >80%, and mean compliance with accelerometer use >80%. A 16-week individualized exercise program for fatigued breast cancer patients did not meet its primary feasibility composite outcome, achieving only 30.3% program adherence.
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