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November 20, 2018Thrombosis and Haemostasis45 citationsOpen Access

Optimizing Stroke and Bleeding Risk Assessment in Patients with Atrial Fibrillation: A Balance of Evidence, Practicality and Precision

MPMarco ProiettiNMNebojša MujovićTPTatjana Potpara

Key Result

Clinical risk scores such as CHA2DS2-VASc and HAS-BLED offer modest but practical predictive value for stroke and bleeding in atrial fibrillation, requiring dynamic reassessment over time.

Structured PICO

P
Population
Patients with atrial fibrillation (AF) requiring evaluation of thromboembolic and bleeding risks for oral anticoagulant therapy.
I
Intervention
Stroke and bleeding risk assessment tools (e.g., CHADS2, CHA2DS2-VASc, ABC-stroke, HAS-BLED)
O
Outcome
Prediction of thromboembolic and bleeding events

Clinical risk scores like CHA2DS2-VASc and HAS-BLED, while having modest predictive ability, remain essential practical tools for dynamic stroke and bleeding risk assessment in AF patients.

Abstract

Optimal stroke prevention using oral anticoagulant (OAC) therapy is essential for the management of patients with atrial fibrillation (AF) who are at increased risk of stroke, but decision making on thromboprophylaxis requires evaluation of individual patient's thromboembolic and bleeding risks.1 Several risk assessment tools have been developed to streamline the evaluation of patients with AF but navigating through the labyrinth of options may be confusing for clinicians.2

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Cite This Study

Proietti et al. (2018) conducted an editorial in Atrial Fibrillation. Stroke and bleeding risk assessment tools was evaluated. Clinical risk scores such as CHA2DS2-VASc and HAS-BLED offer modest but practical predictive value for stroke and bleeding in atrial fibrillation, requiring dynamic reassessment over time.

synapsesocial.com/papers/6a61514e6795803b713f64b6https://doi.org/10.1055/s-0038-1676074
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