Having 6 to 7 ideal cardiovascular health metrics compared to 0 to 2 metrics significantly reduced the risk of all-cause mortality (HR 0.42) and cardiovascular disease mortality (HR 0.10).
Cohort (n=12,538)
Does meeting a greater number of ideal cardiovascular health metrics reduce the risk of all-cause and CVD mortality in middle-aged men?
Meeting a greater number of ideal cardiovascular health metrics is associated with a significantly lower risk of all-cause and cardiovascular disease mortality in middle-aged men.
Hazard Ratio: 0.42 (95% CI 0.31–0.59)
Tasa de eventos absoluta: 2.52% vs 6.83%
valor p: p=<0.001
OBJECTIVES: This study estimated the association of cardiovascular health behaviors with the risk of all-cause and cardiovascular disease (CVD) mortality in middle-aged men in Korea. METHODS: In total, 12 538 men aged 40 to 59 years were enrolled in 1993 and followed up through 2011. Cardiovascular health metrics defined the following lifestyle behaviors proposed by the American Heart Association: smoking, physical activity, body mass index, diet habit score, total cholesterol, blood pressure, and fasting blood glucose. The cardiovascular health metrics score was calculated as a single categorical variable, by assigning 1 point to each ideal healthy behavior. A Cox proportional hazards regression model was used to estimate the hazard ratio of cardiovascular health behavior. Population attributable risks (PARs) were calculated from the significant cardiovascular health metrics. RESULTS: There were 1054 total and 171 CVD deaths over 230 690 person-years of follow-up. The prevalence of meeting all 7 cardiovascular health metrics was 0.67%. Current smoking, elevated blood pressure, and high fasting blood glucose were significantly associated with all-cause and CVD mortality. The adjusted PARs for the 3 significant metrics combined were 35.2% (95% confidence interval CI, 21.7 to 47.4) and 52.8% (95% CI, 22.0 to 74.0) for all-cause and CVD mortality, respectively. The adjusted hazard ratios of the groups with a 6-7 vs. 0-2 cardiovascular health metrics score were 0.42 (95% CI, 0.31 to 0.59) for all-cause mortality and 0.10 (95% CI, 0.03 to 0.29) for CVD mortality. CONCLUSIONS: Among cardiovascular health behaviors, not smoking, normal blood pressure, and recommended fasting blood glucose levels were associated with reduced risks of all-cause and CVD mortality. Meeting a greater number of cardiovascular health metrics was associated with a lower risk of all-cause and CVD mortality.
Kim et al. (Thu,) conducted a cohort in Healthy middle-aged men (n=12,538). 6-7 ideal cardiovascular health metrics vs. 0-2 ideal cardiovascular health metrics was evaluated on All-cause mortality (HR 0.42, 95% CI 0.31 to 0.59, p=<0.001). Having 6 to 7 ideal cardiovascular health metrics compared to 0 to 2 metrics significantly reduced the risk of all-cause mortality (HR 0.42) and cardiovascular disease mortality (HR 0.10).