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January 1, 20134 citationsOpen Access

Early clinical outcomes of the surgical treatment of patients with aortic stenosis and small aortic annuli

GFGrzegorz FilipJKJanusz Konstanty‐KalandykMBMaciej Bochenek

Structured PICO

Does the size of the implanted mechanical aortic valve affect the incidence of patient-prosthesis mismatch and transvalvular gradients in patients with aortic stenosis?

P
Population
92 patients aged 21-74 years with aortic stenosis undergoing surgical aortic valve replacement with St. Jude Medical mechanical aortic valves.
I
Intervention
Surgical aortic valve replacement with St. Jude Medical mechanical aortic valves of varying sizes (small: 17-19 mm, medium: 21-23 mm, large: 25-29 mm).
C
Comparator
Comparison across three groups based on implanted valve size (small vs. medium vs. large).
O
Outcome
Incidence of patient-prosthesis mismatch (PPM) in relation to the size of the prosthetic valves.surrogate

Smaller mechanical aortic valve prostheses are associated with a higher incidence of patient-prosthesis mismatch and higher transvalvular gradients.

Abstract

Background: Aortic stenosis is the most common acquired valvular heart disease. In some patients with small aortic annuli, after the surgical implantation of the artificial aortic valve, pa tient­prosthesis mismatch (PPM) may be observed. It can lead to an increased transvalvular gradient and decreased reduction of left ventricular hypertrophy. PPM is detected in patients with iEOA < 0.85 cm 2 /m 2 . The aim of the study was the evaluation of PPM incidence in relation to the size of the prosthetic valves implanted in patients undergoing aortic valve replacement, as well as the perioperative assessment of treatment results of PPM patients. Material and methods: The study population included 92 patients, aged between 21 and 74 years old, who were implanted with St. Jude Medical mechanical aortic valves. The rate of complications and the echocardiographic parameters were evaluated. Patients were divided into three groups. The first study group consisted of 15 patients who underwent aortic valve implantation and received valves of small aortic annulus diameter (17 mm, 19 mm), the second group included 56 pa tients who received medium-sized valves (21 mm, 23 mm), and the third one consisted of 21 patients who were implanted with valves of large aortic annulus diameter (25 mm, 27 mm, 29 mm). Results: In the first group, PPM was diagnosed in all patients, in the second group in 92.9%, and in the third group in 52%. Perioperative mortality was 5.4%. Average transvalvular gradient in patients with small prostheses was 20.25 mm Hg, in patients with medium prostheses 13.42 mm Hg, and in patients with large prostheses 11 mm Hg.

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Cite This Study

Filip et al. (2013) studied this question.

synapsesocial.com/papers/6a71509431a3df8243298463https://doi.org/10.5114/kitp.2013.38092
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence, Clinical Characteristics and Outcomes of Severe Prosthesis–Patient Mismatch in Patients Undergoing TAVI with Large Aortic Annuli2026
  2. 2Reduction of Left Ventricular Hypertrophy after Aortic Valve Replacement for Isolated Aortic Valve Stenosis1997
  3. 3Application of Regent mechanical valve in patients with small aortic annulus: 3-year follow-up2012 · 4 citations
  4. 4Comparing Clinical Outcomes of Patients With a Small Versus Large Annulus After Newer‐Generation Balloon‐Expandable Transcatheter Aortic Valve Replacement2026
  5. 5Aortic Annulus Enlargement: Early and Long-Terms Results2017 · 7 citations