Transcatheter closure of ventricular septal defect in patients with aortic valve prolapse and mild aortic regurgitation achieved a 96.9% intermediate success rate.
Observational (n=65)
Is transcatheter closure of VSD feasible and safe in patients with aortic valve prolapse and mild aortic regurgitation?
Transcatheter closure of VSD in selected patients with aortic valve prolapse and mild aortic regurgitation is feasible, safe, and can improve valve function at 1 year.
OBJECTIVE: To evaluate the feasibility, safety and efficacy of transcatheter closure of ventricular septal defect (VSD) in patients with aortic valve prolapse (AVP) and mild aortic regurgitation (AR). METHODS: Between January 2008 and July 2014, transcatheter closure of VSD was attempted in 65 patients. RESULTS: The total intermediate closure successful rate in all subjects was 96.9%. During the perioperative period, no death, major bleeding, pericardial tamponade, occluder dislodgement, residual shunt or hemolysis occurred. Two procedures had been forced to suspend due to significant aggregation of device related aortic regurgitation, three cases of transient complete left bundle branch block occurred but did not sustain. At 1-year follow-up, no patients had residual shunts and complications. Furthermore, grade of residual AR were relieved in 61.9% (39/63) cases and degree of AVP were ameliorated in 36.5% (23/63) patients; CONCLUSIONS: Transcatheter closure VSD in selected patients with AVP and mild AR is technically feasible and highly effective. Long term safety and efficacy needs to be assessed.
Chen et al. (2015) conducted an observational in Ventricular septal defect with aortic valve prolapse and mild aortic regurgitation (n=65). Transcatheter closure of ventricular septal defect was evaluated on Intermediate closure successful rate. Transcatheter closure of ventricular septal defect in patients with aortic valve prolapse and mild aortic regurgitation achieved a 96.9% intermediate success rate.