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November 16, 2020Frontiers in Surgery10 citationsOpen Access

Impact of Surgery on Older Patients Hospitalized With an Acute Abdomen: Findings From the Older Persons Surgical Outcome Collaborative

HTHui Sian TayAWAdrian D. WoodBCBen Carter

Key Result

Emergency surgery in older patients hospitalized with an acute abdomen was associated with a significantly increased odds of prolonged hospitalization (aOR 6.60) compared to non-surgical management.

Study Design

Type

Cohort (n=727)

Multicenter

Yes

Structured PICO

Does emergency surgery improve mortality, length of stay, or readmission in older patients hospitalized with an acute abdomen compared to non-surgical management?

P
Population
727 consecutively admitted emergency general surgery patients aged 65 years or older, followed for 90 days.
E
Exposure
Emergency surgery (major or non-major)
C
Comparator
Non-surgical management
O
Outcome
Mortality at Day 30 and 90, length of stay, and readmission within 30 days of dischargehard clinical

In older patients presenting with an acute abdomen, emergency surgery is associated with significantly prolonged hospitalization compared to non-surgical management, without a significant difference in 30- or 90-day mortality.

Main Result

Odds Ratio: 6.6 (95% CI 4.13–10.55)

Absolute Event Rate: 35.1% vs 9%

p-value: p=>0.001

Limitations

  • Data were not collected on the specific diagnoses of the patients, whether surgeries were indicated, or if non-surgical management was chosen due to frailty or multi-morbidity.
  • Potential bias from inter-observer variability.
  • Inability to assess inter-rater variability for the Clinical Frailty Scale.
  • Data were not collected on the diagnoses of the patients, whether surgeries were indicated, or if it was decided to manage patients non-surgically due to frailty or multi-morbidity
  • Potential bias from inter-observer variability
  • Unable to assess inter-rater variability for the clinical frailty scale

Abstract

Background: The impact of surgical operation on older people presenting as general surgical patients compared to non-surgical management is less well researched. Methods: We examined the association between management and adverse outcomes in a cohort of emergency general surgery patients aged>65 years. This multi-center study included 727 patients (mean+/-SD, 77.1±8.2 years, 54% female) admitted to five UK hospitals. Data were analyzed using multi-level crude and multivariable logistic regression. Outcomes included: mortality at Day 30 and 90, length of stay, and readmission within 30 days of discharge. Covariates assessed were management approach, age, sex, frailty, polypharmacy, anemia, and hypoalbuminemia. Results: Approximately 25% of participants (n=185) underwent emergency surgery. Frailty and albumin were associated with mortality at 30 (frailty OR=3.52 95%CI 1.66-7.49, albumin OR=3.78 (95%CI 1.53-9.31), and 90 days post discharge (frailty OR=3.20 95%CI 1.86-5.51, albumin OR=3.25 95%CI 1.70-6.19) and readmission (frailty OR=1.56 [95%CI (1.04-2.35). Surgically managed patients and frailty had increased odds of prolonged hospitalization (surgery OR=5.69 95%CI 3.67-8.80, frailty OR=2.17 95%CI 1.46-3.23). Conclusion: We found the impact of surgery on length of hospitalisation in older surgical patients is substantial. Whether early comprehensive geriatric assessment and post-op rehabilitation would improve this outcome require further evaluation. Keywords: acute surgery, length of stay, mortality, older patients, operation, readmission

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Cite This Study

Tay et al. (2020) conducted a cohort in Acute abdomen / Emergency general surgery (n=727). Emergency surgery vs. Non-surgical management was evaluated on Prolonged hospitalization (> 2 weeks) (aOR 6.60, 95% CI 4.13-10.55, p=>0.001). Emergency surgery in older patients hospitalized with an acute abdomen was associated with a significantly increased odds of prolonged hospitalization (aOR 6.60) compared to non-surgical management.

synapsesocial.com/papers/6a8b0e5e634d203318b1f1f4https://doi.org/10.3389/fsurg.2020.583653
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