Insertion of an aortic valvular homograft in 50 patients resulted in a 6% hospital mortality rate, with no thromboembolic complications and 1 case of significant incompetence at 3 to 12 months.
Observational (n=50)
No
The first 50 cases at the Mayo Clinic of insertion of an aortic valvular homograft after excision of the aortic valve are reported. The hospital mortality rate was 6%. An aortic diastolic murmur was noted in 17% of the surviving patients just prior to their dismissal from the hospital. In none was there evidence of hemodynamically significant aortic valvular incompetence. At follow-up examination 3 to 12 months postoperatively, an aortic diastolic murmur was audible in 44% of the traced patients. Only one patient had hemodynamically significant aortic valvular incompetence. The patients were not given anticoagulant therapy, and there were no thromboembolic complications.
Hoeksema et al. (1967) conducted an observational in Aortic valve disease (n=50). Aortic valvular homograft was evaluated on Hospital mortality rate. Insertion of an aortic valvular homograft in 50 patients resulted in a 6% hospital mortality rate, with no thromboembolic complications and 1 case of significant incompetence at 3 to 12 months.