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August 7, 20250 citationsOpen Access

Corpus-Based Evaluation of Decision-Making in Medical Ethics by Large Language Models

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MEMemi EbaraYKYoshimasa KawazoeTSTomohisa Seki

Key Points

  • Main finding shows that LLMs like GPT-4 and GEMINI surpass random selection in ethical scoring.
  • Key evidence indicates both LLMs scored significantly higher across all ethical principles evaluated.
  • Approach includes a text corpus of 50 clinical scenarios focusing on ethical dilemmas and principles.
  • Significance lies in the potential for future corpus expansion to improve assessment of cultural and institutional ethics.

Abstract

Assessing the ethical biases of large language models (LLMs) is crucial for their clinical application. To evaluate the ethical behavior of LLMs in clinical settings, we introduce a text corpus that focuses on ethical dilemmas. The corpus comprises 50 scenarios of clinical cases, each consisting of a clinical situation and options that impose ethical dilemmas. Each option is scored based on four ethical principles, enabling the evaluation of the ethical decision-making capabilities of LLMs based on their decision trajectories. The GPT-4 and GEMINI LLMs demonstrate significantly higher ethical scores than random selection across all ethical principles. Furthermore, both LLMs demonstrate adaptability to instructions for specific cases, revealing ethical vulnerabilities because they comply with ethically undesirable instructions. Future corpus expansion may allow evaluating diverse cultural and institutional contexts, thereby enhancing ethical evaluation.

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Cite This Study

Ebara et al. (2025) studied this question.

synapsesocial.com/papers/689dfe9fd61984b91e13c505https://doi.org/10.3233/shti250854
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