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September 19, 2025FEBS Letters0 citationsOpen Access

RETRACTION: Evidence That Low Doses of Taxol Enhance the Functional Transactivatory Properties of p53 on p21 Waf Promoter in MCF‐7 Breast Cancer Cells

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Key Points

  • Retraction announced due to significant concerns regarding data integrity from duplicate images.
  • Investigation revealed image duplications in multiple figures, compromising study conclusions.
  • Raw data retrieval was impossible after the time elapsed since original publication in 2006.
  • Authors contested the retraction despite the editors' loss of confidence in the presented data.

Abstract

RETRACTION: M. L. Panno , F. Giordano , F. Mastroianni , C. Morelli , E. Brunelli , M. G. Palma , M. Pellegrino , S. Aquila , A. Miglietta , L. Mauro , D. Bonofiglio , and S. Andò , “,” FEBS Letters 580 , no. ( 2006 ): 2371 – 2380 , https://doi.org/10.1016/j.febslet.2006.03.055 . The above article, published online on 29 March 2006 in Wiley Online Library ( wileyonlinelibrary.com ), has been retracted by agreement between the journal Editor‐in‐Chief, Michael Brunner; FEBS Press; and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation prompted by concerns raised by a third party. The investigation identified inappropriate duplications of image sections in Figures 4, 5, and 10. The authors’ explanation was found to be insufficient to resolve these concerns, and due to the time elapsed since the original publication, the raw data could no longer be retrieved. However, the extent and nature of the inconsistencies identified in the published figures raised significant concerns regarding the data. As a result, the editors no longer have confidence in the integrity of the presented data and consider the study's conclusions to be compromised. The authors do not agree with this retraction.

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Cite This Study

A 2025 study studied this question.

synapsesocial.com/papers/68d466af31b076d99fa6535chttps://doi.org/10.1002/1873-3468.70168
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