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September 23, 2025Taiwanese Journal of Psychiatry1 citationsOpen Access

Associations of Childhood Trauma Exposures with Depressive Symptoms and Moderating Effect of Resilience in Patients with Schizophrenia

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KLK.H. LeePCPei-Yu ChaoCLChien-Wen Lin

Key Points

  • Childhood trauma exposures are linked to depressive symptoms in patients with schizophrenia, especially sexual abuse and emotional neglect.
  • Patients reported an average of 2.8 types of childhood trauma experiences, with resilience showing a negative correlation with depressive symptoms.
  • Cross-sectional analysis included 60 schizophrenia patients, measuring childhood trauma, depressive symptoms, and resilience levels.
  • Findings highlight the need for mental health professionals to assess childhood trauma experiences in schizophrenia management.

Abstract

Abstract Objectives: Both depressive symptoms and childhood trauma exposures compromise mental health in patients with schizophrenia. In this cross-sectional study, we intended to examine the associations between various types of childhood trauma exposures and depressive symptoms as well as to investigate the moderating effect of resilience on the associations in patients with schizophrenia. Methods: We included 60 patients with schizophrenia in this study. Their depressive symptoms, experiences of childhood trauma exposures, level of resilience, and severities of psychiatric symptoms were collected. Results: Patients with schizophrenia in this study experienced many types of childhood trauma exposures (mean ± standard deviation = 2.8 ± 1.4). We found that sexual abuse ( p < 0.05) and emotional neglect ( p < 0.05) were significantly and positively correlated with depressive symptoms, whereas resilience was significantly but negatively correlated with depressive symptoms ( p < 0.001). The strength of the positive association between emotional neglect and depression was decreased in power as the level of resilience was increased. Conclusion: Mental health professionals should routinely assess the experiences of childhood trauma and manage psychological distress caused by childhood trauma exposures in patients with schizophrenia.

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Cite This Study

Lee et al. (2025) studied this question.

synapsesocial.com/papers/68d473a631b076d99fa6be9chttps://doi.org/10.4103/tpsy.tpsy_30_25
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