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September 26, 2025Journal of Clinical MedicineOpen Access

An Updated Meta-Analysis of Randomized Controlled Trials Comparing Direct Oral Anticoagulants Against Warfarin for Left Ventricular Thrombus Resolution

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Authors

JMJ. MagdyMHMaggie HeSASacchin Arockiam

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Overview

Meta-analysis finds no significant difference in LVT resolution between DOACs and warfarin, implying both could be viable options.

Key Points

  • The study finds direct oral anticoagulants are comparable to warfarin for resolving left ventricular thrombus.
  • At 3 months, resolution rates were 86% in the DOAC group vs. 81% in the warfarin group, showing no significant difference.
  • A systematic review of seven randomized controlled trials provided data for this meta-analysis on LVT resolution.
  • Results suggest considering DOACs for patients with left ventricular thrombus resolution, but further trials are needed.

Cite This Study

Magdy et al. (2025) studied this question.

synapsesocial.com/papers/68d6c682b1249cec298b294chttps://doi.org/10.3390/jcm14196735
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