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January 14, 2026Dentistry JournalOpen Access

Microbiological Effects of Laser-Assisted Non-Surgical Treatment of Peri-Implantitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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Authors

CNChariklia NeophytouEVElpiniki VlachodimouEKEleftherios Kaklamanos

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Overview

This systematic review evaluates microbiological outcomes of laser-assisted treatments for peri-implantitis, suggesting implications for personalized dental care.

Key Points

  • The central aim is to assess the microbiological effects of laser-assisted non-surgical treatments for peri-implantitis compared to mechanical debridement.
  • Followed PRISMA guidelines and registered in PROSPERO.
  • Identified randomized controlled trials focusing on microbiological changes associated with laser treatments.
  • Used diode, Er: YAG, and photodynamic therapy lasers in various treatment regimens.
  • Outcomes focused on bacterial counts and risk of bias assessed with RoB2 tool.
  • Quantitative synthesis performed with random-effects meta-analysis.
  • Included eight RCTs with 266 patients and 335 implants.
  • No significant differences in bacterial counts between laser and control groups at 3 and 6 months.
  • PDT showed short-term reductions in specific bacteria for patients with diabetes or acute abscess.
  • Diode and Er: YAG lasers exhibited inconsistent results.
  • Quality of evidence rated as very low according to GRADE.

Cite This Study

Neophytou et al. (2026) studied this question.

synapsesocial.com/papers/6967193f87ba607552bb939fhttps://doi.org/10.3390/dj14010049
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