Population
Women ≥18 years of age presenting with acute myocardial infarction without angiographically obstructive…
Design
Cohort, Core laboratory blinded to clinical, ECG, laboratory, angiographic…
Key result
Plaque disruption was observed in 38% of women with myocardial infarction but no obstructive coronary artery disease, indicating alternate mechanisms of injury.
Authors
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Supports intravascular imaging for plaque disruption in women with MI and nonobstructive CAD; leaves open effects on management.
In women with myocardial infarction and no obstructive coronary artery disease, plaque disruption and ischemic myocardial injury are common mechanisms identified by IVUS and CMR.
Reynolds et al. (2011) studied this question. Plaque disruption was observed in 38% of women with myocardial infarction but no obstructive coronary artery disease, indicating alternate mechanisms of injury.