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September 20, 2001New England Journal of Medicine7,541 citationsOpen Access

Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

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BBBarry M. BrennerMCMark E. CooperDZDick de Zeeuw

Structured PICO

Does losartan improve renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy?

P
Population
Patients with type 2 diabetes and nephropathy
I
Intervention
Losartan
O
Outcome
Renal and cardiovascular outcomes

Losartan provides significant renal benefits and is well tolerated in patients with type 2 diabetes and nephropathy.

Abstract

Losartan conferred significant renal benefits in patients with type 2 diabetes and nephropathy, and it was generally well tolerated.

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Cite This Study

Brenner et al. (2001) studied this question.

synapsesocial.com/papers/69d56c3f75589c71d767cd30https://doi.org/10.1056/nejmoa011161
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Continuum of Renoprotection with Losartan at All Stages of Type 2 Diabetic Nephropathy2004 · 124 citations
  2. 2Losartan: lessons learned from the RENAAL study2006 · 9 citations
  3. 3Losartan and end-organ protection-lessons from the renaal study2005 · 23 citations
  4. 4Losartan2013
  5. 5Losartan in diabetic nephropathy2004 · 28 citations